Urticaria pigmentosa
Urticaria pigmentosa is die mees algemene vorm van kutane mastositose. Dit is ’n seldsame siekte wat veroorsaak word deur oormatige getalle mastselle in die vel; hierdie selle veroorsaak korwe of letsels wanneer die vel geïrriteerd word. Rooi of bruin kolle word dikwels op die vel gesien, gewoonlik rondom die bors, voorkop en rug. Hierdie mastselle, wanneer hulle geïrriteerd word (bv. deur die vel te vryf of hitteblootstelling), produseer te veel histamien, wat ’n allergiese reaksie veroorsaak en lei tot korwe wat gelokaliseer is tot die area van irritasie. Dit word soms verwys na as “Darier se teken”.
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In die 2022 Stiftung Warentest-resultate van Duitsland was verbruikerstevredenheid met ModelDerm net effens laer as met betaalde telemedisyne-konsultasies.
In die 2022 Stiftung Warentest-resultate van Duitsland was verbruikerstevredenheid met ModelDerm net effens laer as met betaalde telemedisyne-konsultasies.
Dit kom geneig voor op die bolyf van jong kinders.
relevance score : -100.0%
ReferencesMastocytose is 'n toestand waarin daar 'n oormaat mastcellen is, wat dikwels in verskeie liggaamsdele soos die vel, beenmurg en spysverteringstelsel voorkom. Volgens die Wêreldgesondheidsorganisasie (WGO) kan kutane mastocytose in drie hooftipes gekategoriseer word. Die eerste tipe (mastocytomas) bestaan uit een of 'n paar (≤3) letsels. Die tweede tipe (urticaria pigmentosa) behels veelvuldige letsels, wat tipies wissel van meer as 10 tot minder as 100. Die laaste tipe toon wydverspreide betrokkeheid van die vel. Urticaria pigmentosa is die mees algemene vorm van kutane mastocytose by kinders, maar dit kan ook by volwassenes voorkom. Dit is gewoonlik 'n onskadelige toestand wat dikwels tydens adolessensie verbeter. Anders as volwasse mastocytose raak urticaria pigmentosa selde interne organe. Een kenmerkende eienskap van urticaria pigmentosa is sy neiging om klein, jeukende, rooibruin of geelbruin kolle of letsels op die vel te veroorsaak, algemeen bekend as korwe. Hierdie kolle verskyn gewoonlik in die kinderjare en kan lewenslank aanhou.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
‘n 6-jarige meisie het ingekom met verskeie donkerkleurige kolle wat eers op haar kopvel verskyn het en daarna oor die afgelope ses maande na haar gesig en lyf versprei het. Sy het gemeld dat die kolle opstaan, rooi word en jeuk wanneer druk daarop uitgeoefen word. Sy het nie koors, brad, diarree of jeuk ervaar nie, en haar persoonlike en familie‑mediese geskiedenis het nie relevante leidrade gegee nie. By ondersoek het ons verskeie donker kolle op haar kopvel, voorkop, gesig en nek gevind, sowel as effens verhewe donker kolle op haar bors en rug. Deur die kolle liggies te vryf, het hulle binne twee minute opgezwol en jeuk, maar die simptome het binne 15–20 minute verdwyn (Darier’s sign).
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
